Here, we use a targeted CRISPR-Cas9 screen of the SLC superfamily to identify SLC25A1 as a critical ferroptosis regulator in human cancer cells. SLC25A1 drives citrate export from the mitochondria to ...

Recommendations for mitochondria transfer and transplantation research Date: January 27, 2025 Source: University of Alabama at Birmingham Summary: Mitochondria organelles came from primordial ...

Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how mitochondria influence the body's immune response through modulating specific cell signaling ...

Examples include magnesium citrate and magnesium glycinate. They may benefit health in a number of ways, from improving blood sugar and blood pressure to reducing anxiety. Magnesium is a mineral ...

Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication 1. These findings ...

State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan 430062, PR China State Key Laboratory of Biocatalysis and ...

Mitochondria are dynamic organelles and central hubs of metabolism whose roles ... to the anti-HER2 monoclonal antibody trastuzumab revealed that resistant cell lines maintained heightened levels of ...

FIGURE 1. Glutathione synthesis in cytosol and compartimentalization in mitochondria. GSH is synthesized from its constituent amino acids in the cytosol by the sequential action of γ-glutamylcysteine ...