This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...
Citrate synthase activity was measured as described by Srere 17. For citrate efflux quantification, 50 plants of each line were germinated on solid media and then transferred to sterile water for ...
Here, we use a targeted CRISPR-Cas9 screen of the SLC superfamily to identify SLC25A1 as a critical ferroptosis regulator in human cancer cells. SLC25A1 drives citrate export from the mitochondria to ...
Many individuals turn to magnesium supplements to meet their requirements and boost their health. Magnesium glycinate and citrate are two common forms of magnesium supplements that are generally ...
Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and ...
In eukaryotes, PUFAs can be de novo synthesized through two independent biosynthetic pathways: the desaturase/elongase pathway and the PUFA synthase pathway. Among them, PUFAs synthesized through the ...
Recommendations for mitochondria transfer and transplantation research Date: January 27, 2025 Source: University of Alabama at Birmingham Summary: Mitochondria organelles came from primordial ...
The changes of mitochondrial network influence the production of reactive oxygen species (ROS) that play an important role in muscle function. Moreover, dysfunctional mitochondria trigger catabolic ...
Correspondence to Dr Meredyth G Ll Wilkinson, Infection, Immunity and Inflammation Research and Teaching Department, UCL, London, WC1N1EH, UK; meredyth.wilkinson.14{at}ucl.ac.uk; Dr Elizabeth C Rosser ...
12 The enzymatic activities of the five respiratory chain complexes were determined in isolated muscle mitochondria extracted from all patients except patients II-1 and IV-2. Activities of the ...