Recent clinical trials with a unique, potent, and selective cholesterol absorption inhibitor (ezetimibe) used in combination with lower doses of various statins showed an additive reduction in ...

Other medications, such as bile acid sequestrants, niacin, and cholesterol absorption inhibitors, may also be used to manage cholesterol levels. In recent years, new classes of drugs, such as ...

which blocks the absorption of cholesterol from food. If the combination of the two does not get the cholesterol levels under ...

Hypercholesterolaemia, characterised by elevated levels of low-density lipoprotein (LDL) cholesterol in the blood, is a major ...

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of ...

Controlling cholesterol absorption is thus crucial for maintaining ... With further advancements, drugs designed to inhibit Aster proteins could work alongside existing therapies, providing ...

Ezetimibe is the only currently FDA-approved approved member of the of intestinal cholesterol reuptake inhibitors drug ... which mediates the absorption of cholesterol from the small intestine.

Figure 5: Cholesterol absorption in wild-type ( ... fed the HF/HC diet (data not shown), which contains cholic acid, an inhibitor of genes encoding cholesterol 7α-hydroxylase.

Approved for use in 2002, ezetimibe works by inhibiting the intestinal absorption ... PCSK9 inhibitors are generally recommended for patients with a family history of high cholesterol.” ...

Combination Therapy Using a Cholesterol Absorption Inhibitor With a Statin The strategy of using a cholesterol synthesis inhibitor to maximize the cholesterol-lowering action of a cholesterol ...