5Department of Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. 6Department of Pharmaco-Therapy, -Epidemiology and- Economy, ...

27) and CIN 3+ (15.7% vs 11.8%, p = .76). No case of CIN 2+ was found in either of 2 patients with ECC diagnosis of CIN 1/2. Therefore, patients with cervical ... 1 high-grade squamous ...

Incidence rates and relative risk of cervical intraepithelial neoplasia (CIN) 1, 2 and 3 in unvaccinated and vaccinated ... doses of HPV vaccine increased with each new birth cohort from 1988 (0.03%) ...

A large majority of high-grade lesions in the female genital ... the vaccine was 100% effective in preventing cervical intraepithelial neoplasia (CIN)1-3 and adenocarcinoma in situ (AIS ...

In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells are already on the path toward malignancy. If left untreated, approximately one-third of these cases progress to cervical ...

“Our findings demonstrate that the therapeutic vaccine Vvax001 is safe, well-tolerated, and effective in eradicating HPV16-associated CIN3 lesions and clearing the underlying persistent HPV16 ...

Cervical cancer in its early stages is easy to treat. For most patients with cervical cancer, treatment continues with regular appointments with the doctor or clinic: In the first 3 years, follow-up ...

Refika Yigit, MD, principal investigator and oncological gynecologist at University Medical Centre Groningen, Netherlands In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells are ...

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical ...