Laurie Adami's experience with CAR T-cell therapy highlights its potential in treating Non-Hodgkin Lymphoma, emphasizing the ...

Researchers have discovered stem-like T cells, enabled by ID3 protein, that combat immune exhaustion in chronic diseases.

Researchers have identified a rare type of immune cells that hold the key to maintaining long-term immune responses.

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to function effectively.

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

Scientists have uncovered a mechanism for reinvigorating the immune system to stop it from flagging when it’s fighting ...

A discovery about the mechanisms that enable the immune system to sustain long-term protection could revolutionize treatment for chronic disease and cancer.

While CAR T therapy has been transformative in treating certain cancers, its effectiveness can wane over time due to T cell exhaustion. Professor Ricky Johnstone, Executive Director Cancer ...

View Full Profile. Learn about our Editorial Policies. Chimeric antigen receptor (CAR) T cell therapy leverages patients’ immune systems to fight cancer. This immunotherapy greatly expanded treatment ...

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its ...