2020年，詹妮弗·杜德纳（Jennifer A. Doudna）教授与埃马纽埃尔·夏彭蒂耶（Emmanuelle Charpentier）共同荣获诺贝尔化学奖，以表彰她们共同开发了基因组编辑方法CRISPR的卓越贡献。 受Frontiers for Young Minds邀请，杜德纳撰文解释了CRISPR的工作原理以及她与合作者是如何发现这一机制的。杜德纳说， ...

expanding CRISPRi targeting scope for functional genomics and enabling efficient screening of repeated genomic elements Type I-E CRISPR–Cas system is one of the most extensively studied RNA ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China ...