DNMT-DNA adducts and 5-aza-dU, produced by DCTD, are sources of DAC-induced DNA damage. DAC-induced DNA damage results in trans-cell cycle cytotoxicity that depends on DNA replication. In this work, ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

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Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Scientists have been working for decades to create synthetic cells that mimic key functions of biological cells. The challenge has been to make the artificial cells dynamic, responsive ...

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The football and basketball betting line look very similar. The most common odds you’ll see in the NBA are with the point spread. In that example, the Bucks are the 4-point favorites ...

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