Blood and histology samples were obtained from both experimental groups at DOL 14 to confirm sequelae of biliary obstruction and quantify F4/80-positive macrophages. Paraffin-embedded liver tissue was ...

Livdelzi (seladelpar) is a medicine that can treat primary biliary cholangitis (PBC) by reducing the amount of bile in your body. It does this by signaling the body to stop making bile acid.

A diagnosis of AIH, PBC, or PSC in a patient with liver disease always requires careful exclusion of other major causes of liver damage, including alcoholic, viral, drug- and toxin-induced ...

A new clinical trial, sponsored by UCL and UCLH, aims to extend survival for some patients with cancer in the biliary tract by treating them with therapies specifically tailored to the genetic profile ...

This investigation of 23 patients with the clinical syndrome of "primary biliary cirrhosis" was undertaken to elucidate the morphologic nature of the hepatic alterations, including their etiology ...

The association between celiac disease and primary biliary cirrhosis is well established. The breakdown of gut–liver axis equilibrium plays a central role in the development of immune disorders ...