However, there is still a big gap in knowledge about the association between gut microbiota associated metabolism alterations and GDM development ... sequencing and high-performance liquid ...

Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

This helps improve fat metabolism by aiding in the breakdown and processing of fat. When gut bacteria produce large amounts of bile acids that activate FXR and reduce bile production, the body ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

They do all this by binding to a receptor called FXR, which acts like a traffic light, controlling cholesterol metabolism and bile acid production to avoid excess buildup." Here's where the ...

They found that those who lost protection also had generally higher levels of bile acids. However, those with remission had higher levels of two specific bile acids, known as lithocholates.

Bile acid metabolism was investigated in 10 patients after cholecystectomy, 10 gallstone patients, and 10 control subjects. Diurnal variations of serum levels of cholic and chenodeoxycholic acid ...

This altered form, called bile acid-methylcysteamine (BA-MCY), inhibits FXR to promote bile production and help boost fat metabolism. "Our study reveals there is a dialogue occurring between the ...