INTERPRETATION/SUMMARY These results: (i) confirm that there are marked regional differences in bile acid metabolism between the right and left halves of the colon, (ii) suggest that caecal and faecal ...

Proinflammatory cytokines stimulate glucocorticoid (GC) release by adrenals but they also inhibit bile acid (BA) efflux from liver. Chronic hepatic inflammation leads to cholestasis and impaired GC ...

Objective There are altered mucosal functions in irritable bowel syndrome with diarrhoea (IBS-D); ~30% of patients with IBS-D have abnormal bile acid (BA) metabolism (ABAM) and diarrhoea (summarised ...

As important metabolic substrates, branched-chain amino acids (BCAAs) and fatty acids (FAs) participate in many significant physiological processes, such as mitochondrial biogenesis, energy metabolism ...

Scientists at Michigan Medicine have made a significant breakthrough in treating nonalcoholic fatty liver disease (NAFLD), a ...

Incorporating anti-inflammatory herbs into daily beverages can help reduce inflammation and promote healing. Notable herbs ...

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China ...

本研究表明，阿来昔诺在治疗 MASH 和相关 HCC 方面具有显著疗效。它能够改善脂质代谢，减轻肝脂肪变性，调节胆汁酸代谢，增加胆汁酸合成和排泄，同时减少肠道重吸收。阿来昔诺还改变了肠道微生物群的组成，增加了阿克曼菌的丰度，且微生物群与胆汁酸代谢之间存在密切关联。此外，阿来昔诺减轻了 MASH 相关的炎症、肝损伤和纤维化，有效预防了 MASH 进展为 HCC。 目前针对 MASH ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Medically reviewed by Melissa Nieves, LND Magnesium is an essential mineral involved in more than 300 reactions in the body.

Investigator Award has been awarded to two surgeon-scientists at the National Cancer Centre Singapore (NCCS) to pursue novel research in liver cancer and head and neck cancers. Globally, liver cancer ...

Be it on a toast or on a plain paratha, butter is an integral part of every Indian diet- traditional and modern, both.