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Aro Biotherapeutics, a clinical-stage biotechnology company working to develop potent and tissue-targeted medicines, today announced that it has received U.S. Food and Drug Administration (FDA) ...

PMX and its polyglutamated derivatives inhibit thymidylate synthase (TYMS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide ... These findings suggest that increased TYMS mRNA and ...

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.

Our study found that the expression of ASS1 in GBM is deficient and high ASS1 expression is associated with poor DFS. Previous research demonstrated that GBM patients with ASS1 methylation had ...

Shares in CureVac have plummeted after a German court ruled that a patent it holds on mRNA-based COVID-19 vaccines was invalid. The validity of the patent is at the heart of patent litigation ...

To perform gene expression analysis at mRNA level, liver tissue was obtained from control individuals (n=21) and patients with liver cirrhosis of different aetiology (n=23). Patient characteristics ...

The human HMGA1 gene, located at the chromosome band 6p21, spans 10 kb and consists of 8 exons, among which only exons 5 to 8 are transcribed in mRNA and code (blue boxes) for the HMGA1 proteins ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

Water and sodium retention during severe hypothyroidism create a state of volume depletion, low extracellular fluid osmolality and increased water retention. The hypothyroid population is ...