In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

In principle, mRNA vaccines are ideal for health emergencies as they can be quickly mass produced using a template. The problem is that current cell-based template production methods take too long, ...

Duchenne muscular dystrophy (DMD) is a rare hereditary disease that is associated with progressive muscle wasting. The ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), ...

The Penn Center for Innovation has enabled world-changing advancements, from mRNA vaccines to CAR T cancer treatments.

Biotechnology company Omega Therapeutics hit Chapter 11 bankruptcy in Delaware on Monday, listing more than $140 million in debt on its petition. The company also filed a form with the U.S. Securities ...

While billions pour into pharmaceutical biotech, officials and experts warn there’s much less private investment in products more relevant to the military, like body armor materials, anti-corrosion ...

On Friday, February 7, a hearing took place in the Montana state legislature on a bill that would ban the use of mRNA ...

Preclinical studies have shown their potential to reduce inflammation and modulate immune responses in diseases like rheumatoid arthritis and lupus.

The model calculations in the present study show that proteins are therefore preferably synthesized in the branched, tapering ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...