A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

In the field of biopharmaceuticals, every technological innovation has the potential to revolutionize treatment strategies. Sanyou Bio's Intelligent Hundred-Trillion Molecule Library (AI-STAL) has ...

1958年，弗朗西斯・克里克提出了中心法则，提出遗传信息从 DNA 转录为 RNA，再经翻译指导蛋白质合成，随后蛋白质参与生命活动这一流程，看似一气呵成，实则存在问题。 若仔细观察，便会发觉此流程不够简洁，RNA 的存在略显累赘。毕竟，越简单的系统往往越高效、越易实现，繁琐的系统则耗能多且不易形成。 从结构看，RNA 与 DNA ...

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

That’s potentially where circular RNA could come in. In fact, rumor is that it could even replace mRNA as it may be more cost-effective to manufacture and is far more durable. Circular RNA is ...

The U.S. government has handed Moderna almost $600 million to accelerate its work on various bird flu vaccines as well as work on mRNA vaccines for other influenza strains with pandemic potential.

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...

Before analyzing mRNA structure, it’s essential to focus on the Coding Sequence (CDS ... Its ability to model complex interactions at the molecular level, visualize the structural components of LNPs, ...