Acetyl-CoA synthetase (ACS) is one of several enzymes that generate the key metabolic intermediate ... enzyme indicates that this acetylation affects the first half-reaction of the ACS catalyzed ...

SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...

Mechanistically, SLC13A2 promotes import of citrate into hepatocytes, serving as building block for ACLY-dependent acetyl-CoA formation and de novo synthesis of cholesterol. In line, the ...

Spanish National Research Council (CSIC), Instituto de Ciencia y Tecnología de Alimentos y Nutrición (ICTAN), Jose Antonio Nováis 6 28040, Madrid, Spain ...

As such, the production of ketone bodies occurs at a site distant from the target. This is of particular importance to the brain, as acetyl-CoA formation, which is largely through β-oxidation, ...

滴铸膜的G因子高达1.30数量级，图案化膜的G因子高达1.06数量级，接近理论极限。通过控制蒸发几何形状，研究组实现了不同形状和尺寸的域，其中超过6平方毫米的同手性域可在左旋和右旋手性之间平滑过渡。

Finally, decreased GAPDH activity activates the polyol pathway, increases intracellular AGE formation ... acids and oxidation of FFA-derived acetyl CoA by the TCA cycle generate the same electron ...

FGF18 increases cartilage formation in rats and may be useful in treating osteoarthritis. The endocrine FGF19 subfamily holds the greatest promise for therapeutic development. These ligands ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Reaction formation may be a temporary coping mechanism, but it’s unproductive in the long run. It ignores underlying beliefs or challenges that need to be addressed, which can hurt mental health.