Oxidative DNA injury is associated with commitment to apoptosis as indicated by caspase-3 expression and TUNEL positivity. The highly significant association between 8-OHdG and caspase-3 ...

Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

TUNEL Assay kit was used to evaluate cardiac apoptosis according to the manufacturer’s protocol (US EVERBRIGHT, T6014). The apoptotic cells were visualized by fluorescence microscopy and apoptosis was ...

Beside developmental abnormalities, it may lead to tumorigenesis, autoimmunity, and other serious health problems. Deregulated apoptosis may also be the leading cause of cancer therapy chemoresistance ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...

2008). The terminal deoxynucleotidyl transferase biotin dUTP nick end labeling assay (TUNEL) for apoptosis was analyzed using a TUNEL kit (Roche, Indianapolis, IN). CD3 was analyzed using mouse ...

The progression of T1DM is significantly influenced by oxidative stress and apoptosis. The natural compound eugenol (EUG) possesses anti-inflammatory, anti-oxidant, and anti-apoptotic properties.

Objectives The circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear ...

Jiangsu Key Laboratory for Biomaterials and Devices, School of Biomedical Sciences and Medical Engineering, Southeast University, Nanjing 210096, P. R. China Department of Cardiology, Nanjing Drum ...