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From Digging Hole In Your Skull To Using Python Bile: Craziest Medical Treatments From Past7. Trepanning: Drilling Holes in the Skull Perhaps the most painful treatment of all. Ancient doctors drilled holes into the skull—a practice called trepanning—to treat pressure in the head.
The most economical method is to cut out a piece of a desired diameter after the fashion of a surgeon when trepanning a skull. The accompanying illustration shows a method of doing this work.
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