A comprehensive study identifies sequence features that predict tissue-specific alternative splicing. In contrast to transcription and translation, in which the flow of information from DNA to pre ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Of particular interest is how kinases integrate extracellular signals with transcription, mRNA splicing, and pathways that control growth and patterning. On a technological front, Dr. Old's lab is ...

The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of Health (grants R01GM130738, R01HG011067 ...

Constitutive splicing is where every intron in the primary RNA transcript is removed as transcription progresses along the gene. Alternative splicing is where exon or intron skipping can occur.