this protein has been found to contribute to some neurodegenerative diseases, broadly defined as tauopathies. Specifically, past research linked the levels of tau in the brains of patients ...

The Swiss pharma group is paying $120 million upfront for exclusive global rights to UCB0107, an anti-tau antibody that is in a phase 1 trial in another disease ... Tau is a protein that ...

pathology is found in a considerable portion of patients with Parkinson's disease (PD), particularly those with early dementia (PDD). Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau ...

a protein that builds up abnormally in Alzheimer’s disease. Blood tests measured levels of other telling proteins, including phosphorylated tau and brain-derived neurotrophic factor (BDNF), which play ...

A characteristic feature of AD is the presence of neurofibrillary tangles, primarily composed of hyperphosphorylated tau protein ... including Pick's disease, progressive supranuclear palsy ...

Department of Chemistry, University of California, Riverside, California 92521, United States ...

Taking longer to drift into the dreaming phase – known as rapid eye movement (REM) sleep – could be an early sign of ...

A defect of either the NPC1 or NPC2 gene results in the protein shortage characteristic of Niemann-Pick type C. As with the other types of Niemann-Pick disease, this is an autosomal recessive disorder ...

Alzheimer’s disease (AD) is the most common tauopathy. Whereas in most tauopathies tau is the only protein that assembles into filaments, in AD intracellular assemblies of tau co-exist with ...