DESPITE the considerable advances that have been made in our knowledge of protein structure ... reflect chemical and physical reactions of secondary importance. These reactions may be avoided ...

tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often involves stepwise establishment of regular secondary and supersecondary structures ...

School of Physics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, P. R. China ...

Introduction Definition of Peptides Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2 to ...

On Nov. 5, the Korea Institute of Materials Science signs a business agreement with Samsung Heavy Industries for cooperation ...

While the idea of a chain of amino acids folding into a working protein might seem simple, it’s a finely tuned process. The folded structure is what allows proteins to carry out the countless ...

It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of proteins, complex molecules that are essential for all life. Next ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

This short manuscript uses mutation counts in phylogenies of millions of SARS-CoV-2 genomes to show that mutation rates systematically differ between regions that are paired or unpaired in the ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

A groundbreaking study combines protein structure with genetic data to trace ancient evolutionary paths, offering a more reliable method to understand the lineage of life. This method could ...

Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The ...