Bile acids (BAs) as cholesterol-derived molecules play an essential role in some physiological processes such as nutrient absorption, glucose homeostasis and regulation of energy expenditure. They are ...

This evidence suggests that PI3K/Akt signaling is involved in the regulation of normal mammary gland growth and breast cancer development ... directly regulates multiple genes that participate in ...

Salmonellae use two type III secretion systems (T3SSs ... that are involved in the remodelling of surface proteins and regulation of virulence genes The intracellular environment induces ...

The standard treatment for HoFH is LDL apheresis combined with maximum tolerated potent statins, ezetimibe and bile acid sequestrants ... in apoB–LP assembly and secretion H Soran has received ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

As the molecular mechanisms underlying zymogen granule (ZG) formation, the sorting/packaging of cargo and regulated secretion/exocytosis ... in host defense and regulation. Validation experiments ...

A teacher at Drakensburg Secondary School in South Africa is under investigation for allegedly cutting off a Hindu student's religious thread. The South African Hindu Maha Sabha has condemned the ...

Correspondence to Dr Séverine Vermeire, Department of Chronic Diseases, Metabolism and Ageing - TARGID, KU Leuven, Leuven B-3000, Belgium; severine.vermeire{at}uzleuven.be IBD is a complex ...