Objective: The C-reactive protein/Lymphocyte Ratio (CLR) is a novel biomarker whose role in the development of chronic kidney disease (CKD) is not well understood. This study aimed to investigate the ...

Lymphocytes are white blood cells that have ... PD-1 and CD73 regulates tolerance by restricting the expansion of auto-reactive CD4 + T cells independently of thymic selection.

Peripheral blood mononuclear cells (PBMCs) from healthy blood donor buffy coat were separated from 10 mL of whole blood on Ficoll-Hypaque density gradients, washed twice in phosphate buffered ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Researchers identify glucose usage as one major divergence betweenT cells expanding in vitro versus those expanding in vivo.

Aptamer-based T Lymphocyte Activity Screening and SEQuencing (ATLAS-seq), to better identify antigen-reactive T cells that are more likely to offer greater immune responses against cancer cells.

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Varicella-zoster virus (VZV) is a known cause of meningoencephalitis, typically in immunocompromised inpatients. We report a ...