The EMBO Journal23 天
SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via ...
SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...
Frontiers18 天
The Implications of PDK1–4 on Tumor Energy Metabolism, Aggressiveness and Therapy Resistance
A metabolic shift from oxidative phosphorylation (OXPHOS) to glycolysis—known as the Warburg effect—is characteristic for many cancers. It gives the cancer cells a survival advantage in the hypoxic ...
Frontiers18 天
Ancient Metabolisms of a Thermophilic Subseafloor Bacterium
The ancient origins of metabolism may be rooted deep in oceanic crust, and these early metabolisms may have persisted in the habitable thermal anoxic aquifer where conditions remain similar to those ...
philstar.com28 天
COA flags P256 million idle rain stations
MANILA, Philippines — The Commission on Audit (COA) has called out the Philippine Atmospheric, Geophysical and Astronomical Services Administration (PAGASA) over P256.07 million worth of ...
BroadwayWorld2 天
Into the Woods Broadway Original Cast
Outstanding Featured Actor - Musical: Robert Westenberg won. Outstanding Featured Actress - Musical: Joanna Gleason won. Outstanding Featured Actress - Musical: Danielle Ferland was nominated but ...
Common Sense Media22 天
Into the Wild
Parents need to know that this long (140 minutes) drama is based on the true story of a college graduate who decided to live off the grid for more than two years, culminating in a fatal four-month ...