The chemistry of amino acid side chains is critical to protein structure because these side chains can bond with one another to hold a length of protein in a certain shape or conformation.

The Nobel Prize in Chemistry is one of the most prestigious ... of how a protein's amino acid sequence dictates its 3D ...

In living organisms, protein molecules with different chemical structures called proteoforms, are produced from a single gene ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

These insights could drive the development of new drugs to treat transthyretin amyloidosis, a progressive and fatal disease.

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Insights into the structures could lead to improved treatment strategies for transthyretin amyloidosis, a progressive, fatal disease in men.

David Baker, Demis Hassabis, and John Jumper share this year’s Chemistry award for their research on protein design and structure prediction. Sneha Khedkar is an Assistant Editor at The Scientist. She ...

Dr Annette Doherty, president of the Royal Society of Chemistry, said of the trio's work: "I add my congratulations to David Baker, Demis Hassabis and John Jumper for their remarkable work on protein ...

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments ...

The oxygen sensor protein ... of Chemistry and Pharmacy and a member of the Centre for Biological Signalling Studies (BIOSS) at the University of Freiburg. His research focuses on the structure ...