Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to elucidate the role of ...

Representatives from four leading companies highlight emerging basic and clinical research that drives renewed optimism.

Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...

When the COVID-19 pandemic first began, we saw how quickly the SARS-CoV-2 virus evolved. New variants emerged with mutations ...

Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...

When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? A ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a ...

Department of Biotechnology, Bhupat & Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India ...

Integrating best practices in AI, genomics, cell culture, and laboratory techniques together contribute to protein expression success.

However, the intricate mechanisms governing these processes have remained elusive due to the presence of multiple functional domains within Munc13, each playing distinct roles in neurotransmitter ...

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...