The linear sequence of amino acids within a protein is considered the primary structure of the protein. Proteins are built from a set of only twenty amino acids, each of which has a unique side chain.

Chaperones can avoid the conformational change to beta sheet structure and the aggregation ... where they will be degraded (Figure 3). Protein aggregation diseases are not exclusive to the central ...

Researchers from Mainz University and EMBL Hamburg present a new approach for structurally characterising disordered proteins ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local ... for deciphering cellular processes and developing targeted therapies for diseases. Proper protein folding is ...

"Many diseases are caused by mutations. Here we show that we can actually start with a gigantic, native protein complex and go all the way down to characterization of its primary structure and ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

They have the potential to attack the body by mistake, which is what happens in autoimmune diseases and allergies. By demonstrating how indispensable this Apex1 protein is to the destructive ...