Background—Fatigue is a frequent and debilitating symptom in patients with primary biliary cirrhosis (PBC). Aims—To study fatigue in relation to sleep, depression, and liver disease severity.

Objective Hepatocellular carcinoma (HCC) is an infrequent yet critical event in primary biliary cirrhosis (PBC); however, predictive tools remain ill-defined. Our objective was to identify candidate ...

Primary biliary cirrhosis (PBC) is a chronic, cholestatic liver disease characterized by progressive destruction of intrahepatic bile ducts, resulting in chronic cholestasis, portal inflammation ...

A diagnosis of AIH, PBC, or PSC in a patient with liver disease always requires careful exclusion of other major causes of liver damage, including alcoholic, viral, drug- and toxin-induced ...

Ipsen has been given accelerated approval by the FDA for Iqirvo, which becomes the first dual PPAR alpha/delta agonist for rare cholestatic liver disease primary biliary cholangitis (PBC).

"Achieving statistical significance on a histology endpoint in compensated ... of the drug under the Ocaliva brand name for primary biliary cirrhosis and cholangitis, with US revenues of around ...

Livdelzi (seladelpar) is a medicine that can treat primary biliary cholangitis (PBC) by reducing the amount of bile in your body. It does this by signaling the body to stop making bile acid.

Gilead Sciences’ Livdelzi (seladelpar) has been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) to treat adults with the rare liver disease primary biliary cholangitis (PBC) ...

Biliary tract disease describes any disease that affects the biliary tract the gall bladder, bile ducts and accompanying structures. Examples include primary sclerosing cholangitis, secondary ...

This will provide specific strategies for the treatment of liver fibrosis and reduce the incidence of cirrhosis and primary liver cancer. This work was supported by the National Natural Science ...

cirrhosis or other liver diseases. The HPA axis controls many functions of the liver through neuroendocrine forward signaling pathways as well as negative feedback mechanisms, in health and disease.

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