The heart drug digoxin could potentially be combined with existing cancer therapies to prevent the spread of tumors, an early ...

The study design comprised measuring the effect of the cardiotonic agent digoxin (a widely used Na+/K+ ATPase inhibitor) in reducing the size of circulating tumor cells clusters, i.e. aggregates ...

The present clinical study, published in the top-tier scientific journal Nature Medicine (link), has shown for the first time that the same effect on clusters can be achieved in humans. A cohort of 9 ...

Windtree Therapeutics, Inc. (NasdaqCM: WINT) showcased encouraging results from the Phase 2b SEISMiC study of istaroxime, its novel investigational therapy for early cardiogenic shock, at the ...

However, TGF-β can also positively impact pulmonary edema. Intriguingly, TGF-β was proposed to increase the function of ENaC, via enhancing the expression of Na+/K+-ATPase α1- and β1-subunits (134). β ...

Soybean cultivar Jidou-7 was obtained from the Institute of Grain and Oil Crops, Hebei Academy of Agricultural and Forestry Sciences, and cultivar Mustang was obtained from Plant Transformation Core ...

Peripheral nerve diseases are traditionally classified as demyelinating or axonal. It has been recently proposed that microstructural changes restricted to the nodal/paranodal region may be the key to ...

The neuroendocrine system is most active at birth and may play a role in the transition from fetal to postnatal life, in particular in the lungs' transition from fluid secretion to fluid absorption.

Unconventional Computing Laboratory, University of the West of England, Bristol BS16 1QY, U.K.

Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases. Study ...