By crystallizing human CHCHD4’s AIF-interaction domain with an activated AIF dimer, we uncover how NADH allosterically configures AIF to anchor CHCHD4’s β-hairpin and histidine-helix motifs to the ...
PNN New Delhi [India] February 1 New Delhi is set to host a historic convergence of creatives innovators policymakers and start-ups as What Design Can Do WDCD presents its first-ever South Asian editi ...
研究人员开发的 AMT 技术,利用修饰的脂肪细胞靶向癌症代谢途径,在多种癌症模型中显著抑制肿瘤生长,减少肿瘤的糖酵解、脂肪酸代谢和尿苷利用,改善缺氧和血管生成情况。脂肪细胞作为一种独特的体外治疗系统,具有诸多优势,如临床获取和移植技术成熟,可通过 CRISPRa 技术进行基因调控,还能与多种癌症治疗方法联合使用。
Indian startups are yet to deliver breakthroughs in the global GenAI race because all service offerings are wrappers around large language models (LLMs), equally available to everyone, said Zerodha ...
Ohio State University has described NADH-ubiquinone oxidoreductase (complex I) inhibitors acting as radiosensitizers for radiation therapy reported to be useful for the treatment of cancer.
It was founded by Nitin Kamath, co-founder of Zerodha. Kailash Nadh, the CTO of Zerodha is also a co-founder of Rainmatter. In 2024, Rainmatter invested ₹275 crore in 47 startups, and it plans to ...