The five phases of mitosis and cell division tightly coordinate the movements of hundreds of proteins. How did early biologists unravel this complex dance of chromosomes? The most obvious ...

The study titled "Chromosome-scale genome dynamics reveal signatures of ... Another mechanism contributing to genetic ...

We have visualized the spatial arrangements of homologous chromosomes and sister chromatids and tracked the movement of a particular chromosome in dividing cells. Our method will facilitate ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Kinetochore capture by spindle microtubules and the subsequent chromosome movements occur via highly dynamic microtubules that maintain kinetochore attachment during significant microtubule turnover.

with no molecular movement, and could potentially contain a more complete genomic picture. To explore the 3D morphology of the existing chromosomes, Aiden modified an in situ Hi-C protocol, dubbed ...

A study conducted by a research team at the Crick Institute identified important genes on the Y chromosome that regulate ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don’t ...

Researchers at the Crick identified Y chromosome genes essential for sperm development and fertility in mice. The findings reveal how gene deletions impact sperm production and shape, providing ...

In each female cell, one X chromosome must be inactivated—crumpled ... offers insights on the forces that restrict the RNA's movement, with implications for how to treat X-linked diseases ...

This principle can be used to explain and support different cell shapes and the movement of chromosomes during the subsequent phases. Examples of questions to ask students: How might the cytoskeleton ...