Mast cell activation syndrome (MCAS) is a condition in which mast cells—a type of white blood cell that plays a key role in ...

A British GP has issued a warning about a lifelong medical condition that often presents 'unexplained' symptoms and can be ...

At the recent AAAAI/WAO meeting, Blueprint Medicines Corp. presented the in vitro and in vivo characterization of BLU-808, a selective inhibitor of wild-type KIT, a transmembrane receptor tyrosine ...

The following is a summary of “Novel Bradykinin Detection In The Diagnostic Workup Of Patients With Recurrent Angioedema ...

A doctor has issued a warning about a lifelong medical condition that can cause 'unexplained' symptoms and is frequently misdiagnosed. It can sometimes be mixed up with fibromyalgia - which millions ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Caroline Cray was diagnosed with mast cell activation syndrome in May 2019 after repeated anaphylactic episodes Jordan Greene is Society and Culture writer-reporter at PEOPLE. She has been working ...

In addition to mast cell activation symptoms, advanced SM is associated with organ damage due to mast cell infiltration and poor survival. AYVAKIT (avapritinib) is approved by the U.S. Food and ...

with emerging strategies focusing on reducing mast cell numbers, inhibiting activation pathways, and suppressing degranulation. 1,5 Patients with CSU often face diagnostic delays, as symptoms may ...

Researchers from Shenzhen University have evaluated the potential antiallergic effects of the histone acetyltransferase KAT6A inhibitor WM-1119 on IgE-mediated mast cell activation and allergic ...

Allergic inflammation plays a big role in allergy reactions and contributes to the itching and chewing commonly seen with ...