In this article we will focus on recombinant production of IgM molecules. We will highlight current achievements and shortcomings of recombinant expression in the mammalian cell system as well as ...

The cytochalasins—a group of mould metabolites—inhibit movement and cytoplasmic cleavage in cultured cells. At higher doses they cause nuclear extrusion which may lead to total enucleation ...

Harris, H., and Watts, J. W., Proc. Roy. Soc., B, 156, 109 (1962).

Additionally, among all the coexpressing cells in the normal digestive system and lung, the expression of ACE2 was relatively highly expressed in the ileum and colon. Conclusion This study provides ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

Here we present an overview and user benefits of CELL HANDLER 2. CELL HANDLER™2 is a cell picking and imaging system that contributes to the efficiency and sophistication of research and ...

Total RNA was extracted from cells using TRIzol reagent and reverse transcribed with Maxima Reverse Transcriptase according to the manufacturer’s instructions. Quantitative PCR analysis was carried ...

1Department of Obstetrics and Gynecology, Peking University Third Hospital, China 2Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, China. 3Biobank, Peking ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, College of Chemistry and Materials, Fudan ...

For decades, two-dimensional cell culture has been regarded as a major tool in cellular and molecular biology due to its simplicity, reproducibility and reliable nature. However, it is now recognized ...

This lock stops the immune system from detecting and eliminating these cells, allowing them to resist treatment. This contrasts with senescent cells, which are highly inflammatory and use ...