Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation ...

Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and ...

Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California 93106, United States Biomolecular Science and Engineering Program, University of California ...

HK-1, hemokinin-1; G6PD, glucose 6-phosphate dehydrogenase; PKM, glycolytic enzyme pyruvate kinase M; MCT1, monocarboxylate transporters 1; LDH, lactate dehydrogenase; PDH, Pyruvate dehydrogenase; SDH ...