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靶向 Il10 和 Il4 信号的诱饵受体可减轻 Aβ 积累,为阿尔茨海默病治疗 ...
为探究免疫信号对阿尔茨海默病(AD)影响,研究人员靶向 Il10 和 Il4 信号,发现诱饵受体可减轻 Aβ 积累,提供新治疗思路。 研究人员在研究中用到了多种关键技术方法。首先,他们使用了腺相关病毒(AAV)技术,将编码可溶性 Il10 受体(sIl10R)和可溶性 Il4 受体(sIl4R)的基因导入小鼠大脑。其次,运用 RNA ...
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