Acute and chronic liver injury models were performed in wild type and Trem-2-/-mice. Primary liver cells from both genotypes of mice were isolated for in vitro experiments. Results TREM-2 was ...

The liver is composed of parenchymal cells (hepatocytes) and non-parenchymal cells, with liver non-parenchymal cells mainly encompassing LSEC, hepatic stellate cells, Kupffer cells, and immune cells.

Discover how integrating advanced imaging, digital pathology, and molecular analysis, can refine fibrosis staging and ...

The different mechanisms by which cholestatic and parenchymal liver disease can lead to reduced bone mass, the prevalence of osteopenia and osteoporosis in patients with early and advanced liver ...

The liver, located in the upper right side of the abdomen, is the body’s largest organ and one of the most important. The liver performs hundreds of vital functions, including converting ...

Treatment did not produce any signs of improvement in liver function; however, histological examination revealed an improvement in portal inflammation, parenchymal alterations and necrosis.

We explore how consumption heterogeneity affects the international transmission mechanism of monetary shocks and the choice of optimal monetary policy in an open economy. Incorporating two types of ...

Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented.