Company to submit sNDA around the end of 1Q 2025 seeking traditional approval of FILSPARI® (sparsentan) for FSGS Net product sales of FILSPARI totaled $50 million in 4Q 2024; $132 million for full yea ...

The data analysis is led by a team from the Michigan Kidney Translational Medicine Center at the University of Michigan. Some Endothelin Receptor Antagonists (ERAs) have caused elevations of ...

Company completed Type C meeting with FDA, aligning on its plan to submit an sNDA; submission expected around end of 1Q25If approved, FILSPARI ...

Hepatotoxicity is damage or injury to the liver as a result of damaging or destructive agents such as drugs or industrial chemicals which are termed hepatotoxins. This study reveals that ...

†Data from lapatanib-treated patients with metastatic breast cancer [43,93]. ‡Data from pazopanib-treated patients with renal cell carcinoma [31]. §This is a definition of a possible Hy's law ...

Taken together, PMI’s preclinical and clinical data constitute a concerning pattern of possible hepatotoxicity, especially considering the short period of exposure. These findings indicate IQOS may ...

manchester.ac.uk Background Patients with rheumatoid arthritis (RA) who take methotrexate (MTX) are advised to limit their alcohol intake due to potential combined hepatotoxicity. However, data are ...

Criticism over how the Chinese government buys drugs for its public health care system has ignited frustration over the quality of medicine. By Alexandra Stevenson and Zixu Wang Reporting from ...

Amoxicillin is a semi-synthetic penicillin that became available in 1972. Amoxicillin and penicillin (also known as penicillin V potassium or penicillin G) are widely prescribed antibiotics used to ...

It’s time to move on from treating heroin as Europe’s main drug problem, according to the head of the European Union’s drugs agency. That’s not to say heroin isn’t still a major problem.

Doctors are sounding the alarm about a common antibiotic taken by millions that is linked to a number of deaths and extreme reactions. Taken by about 3million Americans every year, Bactrim is ...