In this study, we investigated T cell homeostasis and telomeric DNA damage and repair machineries in cART-controlled HIV patients at risk for inflammaging. We found a significant depletion of CD4 T ...

What you need to know ### BMJ Learning To obtain accredited continuous professional development points, subscribers to BMJ Learning can complete the full module at The module contains seven ...

首个专门针对清除潜伏HIV-1细胞的T细胞受体（TCR）疗法已经通过了初步临床试验。这种双特异性免疫疗法可以靶向并清除那些长期携带HIV的CD4+细胞，也就是所谓的“病毒储存库”。

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

After budding and release from infected donor cells, HIV could be able to enter the target cells via two distinct pathways. (left) Entry through endocytic pathway: immature virions interact with the ...

The "Human Immunodeficiency Virus (HIV): Epidemiology Forecast to 2033" report has been added to ResearchAndMarkets.com's offering. This report provides an overview of the risk factors, comorbidities, ...

衰老对免疫系统的多重影响，不仅改变了其组成结构，还可能提升感染、恶性肿瘤及炎症性疾病的风险。随着全球60岁以上人口的显著增长，衰老对免疫相关疾病的影响愈发显著。在免疫系统中，与年龄相关的显著变化包括幼稚与记忆T细胞比例的改变，特别是衰老T细胞如IL- ...

Analysis Reveals an Additional Mechanism Behind Statin Therapy's Heart-Related Benefits in People With HIV Dec. 11, 2024 — Investigators who previously found that a daily statin pill helps ...

随着创新药物的发展和抗逆转录病毒治疗的广泛应用，尤其是鸡尾酒疗法的不断优化，HIV感染者的预期寿命逐步延长。一项对20多万北美和欧洲成年HIV感染者的研究结果表明，CD4+T细胞（HIV病毒主要攻击的人体细胞）计数和年龄对预期寿命的影响最大 [2]— ...

Pseudoscience has recently re-emerged in the U.S. While much of it concerns vaccines, an "oldie" is again making the rounds: ...

Mariam Msemwa clutched her clinic card tightly as she stood in line at Bagamoyo District Hospital's HIV Clinic in Tanzania's ...

A key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T cell. Dysregulated CD4 T cells have been implicated in autoimmune liver disease ...