CPT1 and hypoxia-inducible factor-2α (HIF-2α) also participate in the FAO pathway, promoting Treg differentiation. Acetyl-coenzyme A carboxylase 1 (ACC1) not only promotes the fatty acid synthesis ...

Metabolic requirements of dividing hepatocytes are prerequisite for liver regeneration after injury. In contrast to transcriptional dynamics during liver repair, its metabolic dependencies remain ...

This study provides useful insights into the ways in which germinal center B cell metabolism, particularly lipid metabolism, affects cellular responses. The authors use sophisticated mouse models to ...

2015) on all ATAC-seq-defined OCRs for each cell type. We assessed cell-type-specific enrichment of GWAS signals in four main categories of genomic regions (Figure 1A): (1) Total OCRs: open chromatin ...

The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer.

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