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HIF-1α exerts both detrimental and beneficial actions in atherosclerosis. While there is evidence that HIF-1α could be pro-atherogenic within the atheromatous plaque, experimental models of ...

Various injury factors, including viral infection, alcohol, obesity, and insulin resistance, act on the liver, causing liver inflammation, an immune response, hypoxia, oxidative stress, hepatocyte ...

Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented.