Coordination of cell cycle with metabolism exists in all cell types that grow by division. It serves to build a new cell, (i) fueling building blocks for the synthesis of proteins, nucleic acids, and ...

Itaconate is a crucial anti-infective and anti-inflammatory immunometabolite that accumulates upon disruption of the Krebs cycle in effector macrophages undergoing ... Mesaconate downregulates ...

A Nobel Prize, of course. Such was the case for Hans Krebs, the biochemist who nabbed the award in 1953 for discovering the citric acid cycle, or “Krebs cycle”—the cellular pathway that converts ...

Request permissions for this article.

The cycle of abuse includes four stages—tension building, abuse, reconciliation, and calm—that allow abusers to control their victims through fear and manipulation. This pattern can trap victims and ...

Mitochondrial dysfunction is involved in numerous diseases and the aging process. The integrated stress response (ISR) serves as a critical adaptation mechanism to a variety of stresses, including ...

New mobile apps from the Chinese artificial intelligence (AI) company DeepSeek have remained among the top three “free” downloads for Apple and Google devices since their debut on Jan.

This switch to glycolysis for ATP synthesis, called the Warburg effect ... Restitution of pyruvate dehydrogenase activity enables the irreversible oxidation of pyruvate to acetyl-CoA, which can then ...