(E) Joint pathway analysis based on metabolomics and transcriptomics data. (F) Map of essential genes involved with cystine/cysteine metabolism. Upregulated genes in JIMT1 are highlighted in red and ...

Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...

Since several metabolic pathways are closely tied to T cell and macrophage differentiation, a better understanding of metabolic alterations in immune disorders could help to restore and modulate ...

Here we review current knowledge of the roles of lipid metabolism and function in the CNS and discuss how modulating these pathways may offer novel therapeutic options for treating ALS. Lipids are ...

From the GO analysis, we screened the upregulated differentially expressed genes and identified key pathways, including mitophagy, autophagy, ferroptosis, apoptosis, nonalcoholic fatty liver disease ...

The MEP pathway is an essential part of the energy metabolism of several bacteria, including the hospital germ Pseudomonas aeruginosa. If the MEP pathway in bacteria is blocked, for example by a ...

A new technology is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions. The technology, FISH-scRACS-seq (Fluorescence In Situ ...

Conclusion Oxidative stress, especially through purine metabolism pathway, is a major metabolic event during reperfusion and may contribute to the ischaemia reperfusion injury of lung grafts. Data are ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...