Background: Parkinson’s disease (PD) is a progressive neurodegenerative condition that primarily affects motor functions; it is caused by the loss of midbrain dopaminergic (mDA) neurons. The ...
Myelinated axons are present in sensory neurons and motor neurons, but not all sensory and motor neurons are myelinated. Most neurons that carry signals regarding movement and higher-level functions, ...
To summarize, guided by work in experimental animals, the available evidence in humans, although limited, points toward emerging network dysfunction in a hippocampal–striatal–midbrain network that is ...
Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...
Their potential applications include disease modeling, drug screening, and personalized medicine as they closely mimic the structure and function ... signals in midbrain organoids, demonstrating ...