An exploratory objective assessed VK0214's effects on plasma levels of very long-chain fatty acids (VLCFAs), the biomarkers ...

HSCT may be a suitable treatment for X-linked ALD adults with early signs of cerebral involvement. Very long-chain fatty acid levels and adrenoleukodystrophy protein (ALDP)-deficiency are strongly ...

Quentin M. Anstee, B.Sc., M.B.B.S., Ph.D., M.R.C.P.; Ann K. Daly, B.Sc., Ph.D.; Christopher P. Day, B.A.,M.B., B.Chir.,M.A. (Cambridge), Ph.D.,M.D., F.R.C.P., F.Med ...

In individuals with ALD, levels of short-chain fatty acids (SCFAs), typically ... The production of bile acids (BAs) is regulated by the farnesoid X receptor (FXR); however, alcohol diminishes ...

"ALD is a disease that prevents the body from breaking down long-chain fatty acids, causing them to build ... their son had X-linked Adrenoleukodystrophy, or ALD, a rare and serious genetic ...

Many people would like to delay or even stop the aging process. Previous clinical studies have shown that a reduced calorie intake can slow down the aging process in humans.

Short-chain fatty acids (SCFAs) serve as key signaling molecules linking gut microbiota and host health. Microbially produced ...

ALD prevents the body from breaking down very long chain fatty acids (VLCFAs ... treatment options in the next five to 10 years. X-Linked Adrenoleukodystrophy (ALD) is a rare genetic disorder ...

plasma levels of very long-chain fatty acids (VLCFAs) and other lipids were significantly reduced compared to placebo. VLCFAs ...

Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds ...

Hepatologists, specialists in liver diseases, differentiate between alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). While NAFLD involves the fatty degeneration of ...

ALD prevents the body from breaking down very long chain fatty acids (VLCFAs) which causes damage to the myelin sheath, the membrane that surrounds nerve fibers in the brain and spinal cord.