Fatty acid synthase (FASN), an enzyme that drives de novo lipogenesis, plays a relevant role in metabolic disorders such as obesity, non-alcoholic fatty liver disease (NAFLD) or type 2 diabetes.

They're actually a mixture of different saturated fatty acids, which vary in length depending on the number of carbon atoms in their chains. The types of saturated fats include: The foods you eat ...

The sterol regulatory element-binding transcription factor 1 (SREBP-1), PPAR-γ coactivator-1α (PGC-1α), sirtuin 1 (SIRT1), fatty acid synthase (FASN), farnesyl-diphosphate farnesyltransferase 1 ...

Omega-3 fatty acids are one of two types of polyunsaturated fatty acids. Due to their anti-inflammatory properties, omega-3 fatty acids are considered the healthier type. Omega-3 fatty acids are found ...

The company's lead candidate, denifanstat, is an oral fatty acid synthase (FASN) inhibitor that has shown promising results in clinical trials for NASH treatment. Denifanstat has emerged as a ...

All metabolite identifications were performed using the in-house database (Shanghai Applied Protein Technology). 2.8 Acetyl coenzyme a carboxylase (ACACA), fatty acid synthase (FASN), and carnitine ...