Patch-clamp electrophysiology of giant plasma membrane vesicles (GPMVs) measures MscL pressure sensitivity. A) Schematic representation of GPMV formation. Human bone osteosarcoma epithelial cells ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

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Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

A combined approach involving aspects of both methods is increasingly utilized in the electrophysiology laboratory. A truly integrated approach based on a direct correlation between anatomic ...

The US Food and Drug Administration (FDA) announced its approval of a non-opioid treatment for moderate–severe acute chronic ...

Cardiac ischemia/reperfusion disrupts plasma membrane integrity and induces various types of programmed cell death. The ESCRT (endosomal sorting complex required for transport) proteins, particularly ...

An engineered Lro1 with derepressed activity promotes the turnover of phospholipid-driven ER membrane expansion. The activity of Lro1 is regulated by diacylglycerol produced by Pah1, a conserved ...

really important to maintain any structure which has a membrane," Singh said. Take the electrolyte potassium, for example. It is the most abundant positively charged ion inside cells, but its ...