在医学研究的广阔领域中,多发性硬化症(Multiple Sclerosis,MS)一直是备受关注的难题。这是一种影响中枢神经系统(Central Nervous System,CNS)的自身免疫性疾病,就像身体内部的 “反叛军” 攻击了中枢神经系统的 “城堡”,导致免疫细胞浸润、炎症性脱髓鞘以及轴突损伤等一系列问题。目前,虽然大约有十种疾病修正疗法(Disease - modifying ...
Background Choroid plexus (CP) enlargement has been suggested as a reliable marker of neuroinflammation in adult multiple sclerosis (MS). We investigated CP volume in patients with paediatric MS ...
At just 125 cells per mouse, the dural Treg population was tiny but unmistakable. This scarcity is par for the course for Tregs, which exist in slightly smaller proportions in the spleen. The dural ...
They confirmed this by identifying choroid plexus cells, the cell type that secretes cerebrospinal fluid into the ventricles of the brain, as the gateway for neuro-invasion. "The passage of ...
Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of infection, these so-called Tregs restrain the immune system to ensure it ...
Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.
Human cerebral organoid (CO) is a three-dimensional (3D) cell culture system that recapitulates the developing human brain. While CO has proved an invaluable tool for studying neurological disorders ...
With the consistent occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the prevalence of various ocular complications has increased over time. SARS-CoV-2 infection ...
Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...
Feb. 12, 2025 — Scientists have uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum ...
A Chinese study, led by Arnold ASH Chee, AFCOphthHK, found that a tyrosine kinase inhibitor achieved both durable disease control and visual improvement in patients with epidermal growth factor ...