Combination Therapy Using a Cholesterol Absorption Inhibitor With a Statin The strategy of using a cholesterol synthesis inhibitor to maximize the cholesterol-lowering action of a cholesterol ...

Hypercholesterolaemia, characterised by elevated levels of low-density lipoprotein (LDL) cholesterol in the blood, is a major ...

Recent clinical trials with a unique, potent, and selective cholesterol absorption inhibitor (ezetimibe) used in combination with lower doses of various statins showed an additive reduction in ...

High cholesterol levels can be very dangerous and can even lead to heart diseases. The signs are usually not obvious, but ...

Figure 5: Cholesterol absorption in wild-type ( ... fed the HF/HC diet (data not shown), which contains cholic acid, an inhibitor of genes encoding cholesterol 7α-hydroxylase.

She has spent most of her career counseling patients with diabetes, across all ages. Cholesterol is a waxy substance made by your liver and found in foods like meat, dairy, and tropical oils.

In OCEAN(a)-DOSE, most patients were already on other therapies, including statins, PCSK9 drugs, and cholesterol absorption inhibitor ezetimibe. "Epidemiological research has shown us that Lp(a ...

FH is a genetic condition of very high cholesterol levels that presents a high risk for coronary artery disease.

Citation: Clinical trial finds RNA inhibitor effectively reduces 'bad cholesterol' in patients with cardiovascular disease (2025, February 12) retrieved 18 February 2025 from https://medicalxpress ...

Feb. 3, 2025 — Low-density lipoproteins (LDL) -- commonly known as bad cholesterol -- have long been on scientists' radar as a major contributor to heart disease. But these microscopic ...