expanding CRISPRi targeting scope for functional genomics and enabling efficient screening of repeated genomic elements Type I-E CRISPR–Cas system is one of the most extensively studied RNA ...

The CRISPR-Cas system has emerged as a powerful tool for plant biotechnology, with the potential to improve plant tolerance and resistance to biotic and abiotic stresses, as well as enhance crop ...

NanoCas is the first ultracompact CRISPR system capable of efficient extrahepatic ... NanoCas is a novel Cas enzyme (approximately one-third the size of Cas9) that can be accommodated within ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Complementary discoveries have the potential to enhance treatment options for antibiotic-resistant infections. Researchers at ...

A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...