Gene-editing tools such as CRISPR/Cas9 can be used to create isogenic cell lines, which can be further used to model a specific patient population. An isogenic cell line was created to model ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...

Horizon has created a library of ready-made isogenic human cell line pairs edited using CRISPR-Cas9 technology. With 10,000 gene targets available — 3,000 of them off-the-shelf — the knockout ...

ANALYTICAL SERVICES ON CRISPR/CAS9 EDITED CELL LINES FINGEEC provides following analytical services ... "The xx analysis of xx (genes/KO/KIs) was performed by Finnish Genome Editing Center (FinGEEC), ...

No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...

The second tool is the CRISPR-Cas9 system, which allows easy and precise editing of any region of the genome. When it comes to traditional immortalized cell lines, such as HeLa or HEK293, cutting with ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

Mammoth Biosciences researchers have developed NanoCas, an ultracompact CRISPR nuclease, demonstrating its ability to perform ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...