Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...

Overall, these findings illustrate that miR-128-3p inhibits PDZK1 expression, thereby inhibiting the membrane localization of MRP2 in EIC. Enhancing or restoring PDZK1 expression might therefore have ...

Livdelzi (seladelpar) is a medicine that can treat primary biliary cholangitis (PBC) by reducing the amount of bile in your body. It does this by signaling the body to stop making bile acid.

The dengue virus, a member of the family Flaviviridae, is transmitted by Aedes mosquitoes and causes a viral disease known as dengue fever that is prevalent in tropical and subtropical regions. It is ...

A new clinical trial, sponsored by UCL and UCLH, aims to extend survival for some patients with cancer in the biliary tract by treating them with therapies specifically tailored to the genetic profile ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

The process by which benign conditions cause elevations in CA 19–9 remains unclear. However, it is believed that the presence of biliary stasis or inflammation can lead to obstruction of the biliary ...

This investigation of 23 patients with the clinical syndrome of "primary biliary cirrhosis" was undertaken to elucidate the morphologic nature of the hepatic alterations, including their etiology ...

Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure to diagnose and treat problems in the liver, gallbladder, bile ducts, and pancreas. It combines X-ray and an endoscope—a long, ...

This ultimately leads to biliary complications including cirrhosis, cholangiocarcinoma, and eventually death. Given the uncertainty surrounding the pathogenesis of the disease, a number of ...