Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

Our gut is a bustling hub of activity, home to trillions of microbes that work together with our bodies to keep us healthy. A recent study explores one fascinating aspect of this partnership: how gut ...

They do all this by binding to a receptor called FXR, which acts like a traffic light, controlling cholesterol metabolism and bile acid production to avoid excess buildup." Here's where the ...

This helps improve fat metabolism by aiding in the breakdown and processing of fat. When gut bacteria produce large amounts of bile acids that activate FXR and reduce bile production, the body ...

The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of ...

This altered form, called bile acid-methylcysteamine (BA-MCY), inhibits FXR to promote bile production and help boost fat metabolism. "Our study reveals there is a dialogue occurring between the ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

They found that those who lost protection also had generally higher levels of bile acids. However, those with remission had higher levels of two specific bile acids, known as lithocholates.